Nanoscale Supramolecular Probes for the Naked-Eye Detection of Illicit Drugs. Daniele Rosa-Gastaldo, Angelo Scopano, Marco Zaramella, Fabrizio Mancin.Pattern-Based Recognition Systems: Overcoming the Problem of Mixtures. This article is cited by 57 publications. Quantitative experiments performed in urine using a new three-way calibration model allows for determination of drugs and their metabolites using one sensor from a single fluorescence reading.
A simple three sensor cross-reactive array enables the determination of drugs and their metabolites in water with high fidelity and low error. Molecular dynamics is employed to understand the nature of the binding interactions. The recognition event between the aCBs and guests results in modification of the fluorescence of the terminal walls, a fluorescence response that can be used to sense the drugs of abuse morphine, heroin, and oxycodone as well as their metabolites. The large hydrophobic binding cavity is flexible and is able to adapt to guests of various size and topology. The connectivity between the glycourils and naphthalene rings largely defines the opening size of the cucurbituril cavity and its diameter. Your old school was probably laid out in a different kind of way, but you get the idea), or around a town (corner shop, roundabout, t-junction, newsagents etc).The present study highlights a sensing approach for opiates using acyclic cucurbituril (aCBs) sensors comprising four glycouril units terminated on both ends with naphthalene fluorophore walls. All the routes I use are either around different rooms of large buildings (my old school provides three routes the first one starts in room 6, then moves onto room 5, room 4, the hallway, the top of the stairs, the bottom of the stairs, the downstairs hallway, room 3, room 2, room 1 and so on. To memorise a pack of cards, then, you first need to think of a journey or route with 26 easily-remembered locations.
If you dont like it, you might prefer to buy the books by Tony Buzan, Dominic OBrien and Andi Bell (although none of them has useless knowledge at the bottom of every page like this one). Lots of people over the years have added their own twists to the basic principles, and the specific system described below is my version. Some people also call it the journey method, because it involves these locations being in a set sequence, and most people like their mental locations to be points on a journey. Its called the location method, and it involves using mental pictures of people or objects in set locations.
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